Guideline | Resources |
tPA in Ischemic Stroke: 2013 ACEP Clinical Policy | Epocrates Guideline Synopsis |
Key Points
Offer IV tPA to pts meeting criteria who can be treated w/in 3h of sx onset, and consider if w/in 4.5h of sx onset.
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American College of Emergency Physicians. Clinical Policy: Use of Intravenous tPA for the Management of Acute Ischemic Stroke in the Emergency Department. Ann Emerg Med. 2013;61:225–243.
Epocrates Guideline Synopsis Last Update:
Dec 29, 2016
Publication Year:
2013
Source:
ACEP
- American College of Emergency Physicians
Endorsed By:
American Academy of Neurology
Evidence Grade
[A] | Accepted practice; based on supporting Class I studies and/or robust supporting Class II studies |
[B] | May be acceptable; based on supporting Class II studies and/or robust supporting Class III studies |
[C] | Requires further investigation; no adequate supporting Class I or II studies |
Abbreviations
DM | diabetes mellitus |
GI | gastrointestinal |
GU | genitourinary |
IV | intravenous |
MCA | middle cerebral artery |
NIHSS | National Institutes of Health Stroke Scale |
SAH | subarachnoid hemorrhage |
tPA | tissue plasminogen activator |
Evidence Grade
A | = | Accepted practice; based on supporting Class I studies and/or robust supporting Class II studies |
B | = | May be acceptable; based on supporting Class II studies and/or robust supporting Class III studies |
C | = | Requires further investigation; no adequate supporting Class I or II studies |