By makin, 7 October, 2014
By makin, 7 October, 2014
By makin, 7 October, 2014
(BMJ) - A 31-yo woman who had been taking oxytetracycline x 3 mo for rosacea presented w/ painful, yellow nails lifting off the nailbed, which began while she was on vacation in Turkey 3 wks prior. Exam: yellow discoloration and onycholysis of fingernails and toenails. What is the diagnosis?
Paronychia
Leukonychia
Pompholyx
Onychomycosis
Photo-onycholysis
You are correct. Photo-onycholysis is a common photosensitivity side effect of tetracyclines. It may be accompanied by a rash. Sometimes it leads to loss of the nail, but usually regresses spontaneously after stopping the tetracycline. This patient's nails returned to normal after tx was stopped.