By rray, 15 March, 2023 Add therapeutic anticoagulation if large CAA or mod severe LV dysfxn no bleeding risk
By rray, 15 March, 2023 Intensification tx may require dual tx w glucocorticoids plus either anakinra or infliximab Anakinra infliximab should NOT be given in combo
By rray, 15 March, 2023 Give 1 of following anakinra 5 10 mg kg IV SC qd in 1 4 divided doses methylprednisolone2 10 30 mg kg day IV x1 3 days max 1000 mg day infliximab 5 10 mg kg IV x1 dose
By rray, 15 March, 2023 IVIG1 2 g kg IBW dose IV x1 dose max 100 g dose plus methylprednisolone2 1 2 mg kg day IV divided q12h
By rray, 15 March, 2023 Intensification tx recommended if no improvement w in 24h of initial immunomodulatory tx