(BMJ) - A 15-yo girl with bilateral periorbital reddish-purple rash and swelling x 3 months developed a V-neck rash, periungual vascular dilatation, fever, leukocytopenia, polyarthralgia and symmetrical proximal muscle weakness. What is the diagnosis?
Neuroblastoma
Basilar skull fracture
Juvenile dermatomyositis
Lambert–Eaton myasthenic syndrome
Allergic contact dermatitis
You are correct. Periorbital heliotrope dermatitis, V-neck rash, and proximal muscle weakness are useful diagnostic findings in this systemic autoimmune myopathy. Symptoms resolved after prednisone and cyclophosphamide treatment.