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Footnote
<sup>1</sup> <b>AHA 2021.</b> Wilson WR, et al. Prevention of Viridans Group Streptococcal Infective Endocarditis: A Scientific Statement From the American Heart Association. <i>Circulation.</i> 2021 May 18;143(20):e963-e978. <a href=https://www.ahajournals.org/doi/10.1161/CIR.0000000000000969><u>Full-text article</u></a>
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<b>Prophylaxis not recommended</b> for pacemaker/similar implanted electronics, completed closed septal defect devices, peripheral vascular graft/patch (including for HD), coronary/vascular stents, CNS ventriculoatrial shunt, vena cava filter, pledget.
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Four conditions warrant prophylaxis for specific dental/oral surgery procedures:<br>
• <b>Prosthetic cardiac valve/material</b><br>
◦ Prosthetic valve (including transcatheter-implanted)<br>
◦ Valve repair w/ device (e.g., annuloplasty ring/clip)<br>
◦ LVAD or implantable heart<br>
• <b>Previous/relapsed/recurrent IE</b><br>
• <b>CHD</b><br>
◦ Unrepaired cyanotic congenital CHD (including palliative shunt, conduit)<br>
◦ Congenital defect repaired w/ prosthetic material/device (via surgery/transcatheter) w/in 6mo after repair<br>
◦ Repaired w/ residual defects @ site of/adjacent to prosthetic patch/device<br>
◦ Surgical/transcatheter PA valve/conduit<br>
• <b>Cardiac txp w/ valvulopathy</b>
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<sup>2</sup> <b>ESC 2023.</b> Delgado V, et al. 2023 ESC Guidelines for the management of endocarditis: Developed by the task force on the management of endocarditis of the European Society of Cardiology (ESC). <i>Eur Heart J.</i> Preprint. Posted online August 25, 2023.
<a href=https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehad193/7243107><u>Full-text article</u></a>
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<sup>3</sup> <b>JCS 2017. Mod risk:</b><br>
• Non–high-risk CHD including bicuspid aortic valve (however, isolated ASD and repaired VSD/PDA 6+ mo post-op w/o residual shunt deemed low risk)<br>
• MVP w/ regurg<br>
• acquired valvular dz (however, mitral stenosis w/o regurg and functional murmur are deemed low risk)<br>
• hypertrophic cardiomyopathy w/ obstruction<br>
• intracardiac devices (pacemaker, implantable defibrillator)<br>
• chronic central venous catheter
<br><br>
Nakatani S, et al. JCS 2017 Guideline on Prevention and Treatment of Infective Endocarditis. <i>Circ J.</i> 2019 Jul 25;83(8):1767-1809.
<a href=https://www.jstage.jst.go.jp/article/circj/83/8/83_CJ-19-0549/_pdf/-char/en><u>Full-text article</u></a>
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<sup>4</sup> <b>NICE 2016.</b> Prophylaxis against infective endocarditis: antimicrobial prophylaxis against infective endocarditis in adults and children undergoing interventional procedures. National Institute for Health and Care Excellence. Published March 17, 2008. Updated July 8, 2016.
<a href=https://www.nice.org.uk/guidance/cg64><u>Accessed September 7, 2023</u></a>
<br><br>
<b>Prophylaxis not recommended</b> for pacemaker/similar implanted electronics, completed closed septal defect devices, peripheral vascular graft/patch (including for HD), coronary/vascular stents, CNS ventriculoatrial shunt, vena cava filter, pledget.
<br><br>
Four conditions warrant prophylaxis for specific dental/oral surgery procedures:<br>
• <b>Prosthetic cardiac valve/material</b><br>
◦ Prosthetic valve (including transcatheter-implanted)<br>
◦ Valve repair w/ device (e.g., annuloplasty ring/clip)<br>
◦ LVAD or implantable heart<br>
• <b>Previous/relapsed/recurrent IE</b><br>
• <b>CHD</b><br>
◦ Unrepaired cyanotic congenital CHD (including palliative shunt, conduit)<br>
◦ Congenital defect repaired w/ prosthetic material/device (via surgery/transcatheter) w/in 6mo after repair<br>
◦ Repaired w/ residual defects @ site of/adjacent to prosthetic patch/device<br>
◦ Surgical/transcatheter PA valve/conduit<br>
• <b>Cardiac txp w/ valvulopathy</b>
<br><br>
<sup>2</sup> <b>ESC 2023.</b> Delgado V, et al. 2023 ESC Guidelines for the management of endocarditis: Developed by the task force on the management of endocarditis of the European Society of Cardiology (ESC). <i>Eur Heart J.</i> Preprint. Posted online August 25, 2023.
<a href=https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehad193/7243107><u>Full-text article</u></a>
<br><br>
<sup>3</sup> <b>JCS 2017. Mod risk:</b><br>
• Non–high-risk CHD including bicuspid aortic valve (however, isolated ASD and repaired VSD/PDA 6+ mo post-op w/o residual shunt deemed low risk)<br>
• MVP w/ regurg<br>
• acquired valvular dz (however, mitral stenosis w/o regurg and functional murmur are deemed low risk)<br>
• hypertrophic cardiomyopathy w/ obstruction<br>
• intracardiac devices (pacemaker, implantable defibrillator)<br>
• chronic central venous catheter
<br><br>
Nakatani S, et al. JCS 2017 Guideline on Prevention and Treatment of Infective Endocarditis. <i>Circ J.</i> 2019 Jul 25;83(8):1767-1809.
<a href=https://www.jstage.jst.go.jp/article/circj/83/8/83_CJ-19-0549/_pdf/-char/en><u>Full-text article</u></a>
<br><br>
<sup>4</sup> <b>NICE 2016.</b> Prophylaxis against infective endocarditis: antimicrobial prophylaxis against infective endocarditis in adults and children undergoing interventional procedures. National Institute for Health and Care Excellence. Published March 17, 2008. Updated July 8, 2016.
<a href=https://www.nice.org.uk/guidance/cg64><u>Accessed September 7, 2023</u></a>
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Patient Type Detail Header (Long)
Antibiotic prophylaxis isn’t suggested for pts w/o relevant cardiac conditions,<sup>1</sup> per AHA.