Oral theophylline has small bronchodilator effect A and assoc w modest sx benefit B Disadvantages low therapeutic ratio and many toxic effects arrhythmias sz drug interactions others

<b>Oral theophylline:</b> has small bronchodilator effect [A]and assoc w/ modest sx benefit [B]. Disadvantages: low therapeutic ratio and many toxic effects (arrhythmias, sz, drug interactions, others).