Choose tx based on side effect profile in the context of shared decision making CP nbsp nbsp Antimuscarinics common dry mouth constipation voiding dysfunction incomplete emptying retention blurred vision rare palpitations tachycardia and QT prolongation w

By rray, 12 July, 2024
Detail (Long)
Choose tx based on side-effect profile, in the context of shared decision-making. [CP]<br>
&nbsp;&nbsp;◦ <b>Antimuscarinics:</b> common: dry mouth, constipation, voiding dysfunction/incomplete emptying, retention, blurred vision; rare: palpitations, tachycardia, and QT prolongation, which can lead to torsades de pointes. ER superior to IR formulations for &darr; side effects.<br>
&nbsp;&nbsp;◦ <b>β3 agonists:</b> may have fewer side effects than antimuscarinics, esp. dry mouth and constipation, and less effect on PVR, resulting in &darr;rates of voiding dysfunction, but may affect CV function; mirabegron not recommended if severe, uncontrolled HTN (SBP ≥180 mmHg or DBP ≥110 mmHg).