Detail (Long)
Assess tx for efficacy and onset of side effects w/in 4-8wk of tx initiation. [EO]<br>
◦ If intolerable side effects or inadequate improvement: May offer a different medication in the same class or a medication from a different class. [CP] For pts on antimuscarinics, switching to a β3 agonist may be more tolerable, due to apparently lower rates of common side effects, while maintaining efficacy.<br>
◦ If inadequate improvement w/ a single medication: May offer combo tx w/ a medication from a different class—e.g., antimuscarinic + β3 agonist. [CR/B]
◦ If intolerable side effects or inadequate improvement: May offer a different medication in the same class or a medication from a different class. [CP] For pts on antimuscarinics, switching to a β3 agonist may be more tolerable, due to apparently lower rates of common side effects, while maintaining efficacy.<br>
◦ If inadequate improvement w/ a single medication: May offer combo tx w/ a medication from a different class—e.g., antimuscarinic + β3 agonist. [CR/B]