Tx of GAS carriers is not usually recommended [S/M], unless certain community/family factors<sup>7</sup> are present, then treat w/:

By rray, 10 November, 2014
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Footnote
<sup>7</sup> Situations in which eradication of GAS carriage may be desirable: <b>1)</b> community outbreak of rheumatic fever, glomerulonephritis, or invasive GAS; <b>2)</b> outbreak of GAS pharyngitis in closed community; <b>3)</b> family/personal hx of rheumatic fever; <b>4)</b> family w/ excessive anxiety about GAS; <b>5)</b> when tonsillectomy considered only for GAS carriage.
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clindamycin 20-30 mg/kg/day tid (max 300 mg/dose) x10 days [S/H]
penicillin V 50 mg/kg/day PO q6h (max 2000 mg/day) x10 days AND rifampin 20 mg/kg (max 600 mg) PO once/day x last 4 days [S/H]
amoxicillin-clavulanate 40 mg amox/kg/day PO tid (max 2000 mg amox/day) x10 days [S/M]
benzathine penicillin G 600,000 U (if <27 kg) or 1.2 million U (if ≥27 kg) IM x1 AND rifampin 20 mg/kg/day (max 600 mg/day) PO bid x4 days [S/H]