By rray, 15 March, 2023 Give 1 of following anakinra 5 10 mg kg IV SC qd in 1 4 divided doses methylprednisolone2 10 30 mg kg day IV x1 3 days max 1000 mg day infliximab 5 10 mg kg IV x1 dose
By rray, 15 March, 2023 IVIG1 2 g kg IBW dose IV x1 dose max 100 g dose plus methylprednisolone2 1 2 mg kg day IV divided q12h
By rray, 15 March, 2023 Intensification tx recommended if no improvement w in 24h of initial immunomodulatory tx
By rray, 15 March, 2023 Consult w multidisciplinary team for immunomodulatory tx mgmt for children w MIS C which may include cardiology hematology infectious disease intensive care rheumatology
By rray, 15 March, 2023 Consider adding baricitinib2 or tocilizumab if no rapid improvement in oxygenation w in 24h of tx