40 75 yo w DM at higher CVD risk esp w multiple ASCVD risk factors Use high intensity statin to darr LDL C by 50 adding ezetimibe or PCSK9i to max tolerated statin may be reasonable in pts w an LDL C 70 mg dL

<b>40-75 yo w/ DM at higher CVD risk,</b> esp w/ multiple ASCVD risk factors: Use high-intensity statin to &darr; LDL-C by ≥50%; adding ezetimibe or PCSK9i to max-tolerated statin may be reasonable in pts w/ an LDL-C ≥70 mg/dL