If high risk offer specific tx e g antivirals monoclonal Ab to decrease risk of hospitalization and death 4 Monitor closely If immunocompromised consider convalescent plasma w in 8 days of sx onset low certainty of evidence Pts who aren t immunocompromise

<b>If high risk, offer specific tx (e.g., antivirals/monoclonal Ab) to decrease risk of hospitalization and death.⁴</b> Monitor closely. If immunocompromised, consider <b>convalescent plasma w/in 8 days of sx onset</b> (low certainty of evidence). Pts who aren’t immunocompromised would likely place a lower value on the uncertain benefits of convalescent plasma (reductions in need for mechanical ventilation, hospitalization, and death).⁶