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<b>After tx initiation, review, assess, and adjust if needed.</b> Review sx and exac risk (hx and blood eos). Assess inhaler technique and benefits of non-pharm tx (e.g., pulm rehab, self-mgmt education) at every visit. If benefit is documented, continue; otherwise, stop or try alternative BD class. De-escalate tx when appropriate. Any change in regimen requires re-review.