If PSA 4 ng mL or very suspicious DRE bx and further w u indicated 2A 12 Validated risk calculators may be used to inform shared decision making process for prostate bx CR AUA B 6

If PSA >4 ng/mL or very suspicious DRE, bx and further w/u indicated [2A].¹² Validated risk calculators may be used to inform shared decision-making process for prostate bx [CR][AUA-B].⁶