Start short- or long-acting BD1 (long-acting preferred, unless SOB is only occasional): SAMA/LAMA (ipratropium / aclidinium, tiotropium, umeclidinium) or SABA/LABA (albuterol, levalbuterol / arformoterol, formoterol, indacaterol, olodaterol, salmeterol)

<b>Start short- or long-acting BD</b>¹ (long-acting preferred, unless SOB is only occasional): SAMA/LAMA (ipratropium / aclidinium, tiotropium, umeclidinium) or SABA/LABA (albuterol, levalbuterol / arformoterol, formoterol, indacaterol, olodaterol, salmeterol)