By rray, 9 February, 2023 Obesity mgmt wt loss Care goals should include wt loss or prevention of wt gain minimizing progression of hyperglycemia and addressing CV risk B Consider pharmacotherapy to support pt centered goals B Consider more intensive preventive strategies in pts a
By rray, 9 February, 2023 Based on pt preference consider DM technology assisted tools to help prevent delay T2DM onset B
By rray, 9 February, 2023 Stroke MI prevention To lower stroke MI risk consider pioglitazone in pts w stroke hx and evidence of insulin resistance prediabetes Benefit needs to be balanced w increased risk of wt gain edema fx A Lower doses may mitigate ADR risk but may be less effe
By rray, 9 February, 2023 Statin tx may increase risk of T2DM in at risk pts monitor glucose status and reinforce DM prevention in such pts Statin d c isn t recommended B
By rray, 9 February, 2023 Monitor at least annually E for development of T2DM modify freq based on individual risk benefit assessment using informal risk assessment or an assessment tool
By rray, 9 February, 2023 Variety of eating patterns acceptable for pts w prediabetes B including Mediterranean and low carb diets
By rray, 9 February, 2023 Metformin3 4 to prevent T2DM has the strongest evidence and long term safety profile Consider if BMI 35 kg m2 age 25 59 yo FPG 110 mg dL A1C 6 0 or hx of gestational DM A
By rray, 9 February, 2023 Refer adults w overweight obesity at high risk of T2DM pts w IGT IFG 1 or A1C 5 7 6 4 2 to intensive lifestyle behavior change program targeting 7 body wt loss and increasing mod intensity physical activity e g brisk walking to at least 150min wk A