By rray, 22 February, 2024 Oral theophylline has small bronchodilator effect A and assoc w modest sx benefit B Disadvantages low therapeutic ratio and many toxic effects arrhythmias sz drug interactions others
By rray, 22 February, 2024 LAMA options aclidinium glycopyrrolate revefenacin tiotropium DPI MDI umeclidinium
By rray, 22 February, 2024 Start long or short acting BD Long acting preferred unless SOB is only occasional A Inhaled is preferred vs oral A Regular and prn SAMA or SABA use improves FEV1 and sx A SABA SAMA combos more effective than mono tx A LABAs and LAMAs improve dyspnea reduc
By rray, 22 February, 2024 Prescribe rescue short acting BD SABA or SAMA to all pts for immediate sx relief SABA options albuterol levalbuterol MDI NEB SAMA ipratropium MDI NEB
By rray, 22 February, 2024 GOLD. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease. 2024 Report.